Presqualene diphosphate synthase explained

Presqualene diphosphate synthase
Ec Number:	2.5.1.103

Presqualene diphosphate synthase (SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming).^[1] This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate

\rightleftharpoons presqualene diphosphate + diphosphate

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

Notes and References

1. Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii . Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J . Proc. Natl. Acad. Sci. USA . 2011 . 108 . 12260–12265 . 21746901 . 10.1073/pnas.1106222108 . 30 . 3145686. 2011PNAS..10812260N . free .