Polyostotic fibrous dysplasia explained

Polyostotic fibrous dysplasia
Field:	Osteology
Synonyms:	Albright's disease^[1]

Polyostotic fibrous dysplasia is a form of fibrous dysplasia affecting more than one bone.^[2] Fibrous dysplasia is a disorder where bone is replaced by fibrous tissue, leading to weak bones, uneven growth, and deformity. ^[3]

McCune–Albright syndrome includes polyostotic fibrous dysplasia as part of its presentation.^[4] When polyostotic fibrous dysplasia manifests in the long bones, limping results; when it manifests in the face, asymmetric growth of the face can result.

One treatment that has been used is bisphosphonates.^[5]

See also

• Fibrous dysplasia of bone
• Monostotic fibrous dysplasia
• List of radiographic findings associated with cutaneous conditions

Notes and References

1. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
2. Web site: Fibrous Dysplasia: Overview - eMedicine Radiology . 2009-02-23.
3. Web site: McCune–Albright syndrome. Reference. Genetics Home. Genetics Home Reference. en. 2018-10-30.
4. Lee. Peter A.. McCune–Albright Syndrome: Long-term Follow-up. JAMA: The Journal of the American Medical Association. 5 December 1986. 256. 21. 2980–4. 10.1001/jama.1986.03380210076028. 3773215.
5. Khadilkar VV, Khadilkar AV, Maskati GB . Oral bisphosphonates in polyostotic fibrous dysplasia . Indian Pediatr . 40 . 9 . 894–6 . September 2003 . 14530553 .