Polyamine oxidase (propane-1,3-diamine-forming) explained

Polyamine oxidase (propane-1,3-diamine-forming)
Ec Number:	1.5.3.14

Polyamine oxidase (propane-1,3-diamine-forming) (MPAO, maize PAO) is an enzyme with systematic name spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming).^{[1] [2]} This enzyme catalyses the following chemical reaction

spermidine + O₂ + H₂O

\rightleftharpoons propane-1,3-diamine + 4-aminobutanal + H₂O₂

The products of the reaction cannot be converted directly to other polyamines.

Notes and References

1. Tavladoraki P, Schininà ME, Cecconi F, Di Agostino S, Manera F, Rea G, Mariottini P, Federico R, Angelini R . Maize polyamine oxidase: primary structure from protein and cDNA sequencing . FEBS Letters . 426 . 1 . 62–6 . April 1998 . 9598979 . 10.1016/S0014-5793(98)00311-1 .
2. Federico R, Ercolini L, Laurenzi M, Angelini R . Oxidation of acetylpolyamines by maize polyamine oxidase . Phytochemistry . 1996 . 43 . 339–341 . 10.1016/0031-9422(96)00316-0.