Polyamine-transporting ATPase explained

polyamine-transporting ATPase
Ec Number:	3.6.3.31
Go Code:	0015417

In enzymology, a polyamine-transporting ATPase is an enzyme that catalyzes the chemical reaction

ATP + H₂O + polyamineout

\rightleftharpoons ADP + phosphate + polyaminein

The 3 substrates of this enzyme are ATP, H₂O, and polyamine, whereas its 3 products are ADP, phosphate, and polyamine.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (polyamine-importing). This enzyme participates in abc transporters - general.

References

• Kashiwagi K, Miyamoto S, Nukui E, Kobayashi H, Igarashi K . 1993 . Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli . J. Biol. Chem. . 268 . 19358–63 . 8366082 . 26 .
• Kuan G, Dassa E, Saurin W, Hofnung M, ((Saier MH Jr)) . 1995 . Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases . Res. Microbiol. . 146 . 271–278 . 7569321 . 4 . 10.1016/0923-2508(96)81050-3. free .
• Saier MH Jr . 1998 . Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya . Adv. Microb. Physiol. . 40 . 81–136 . 9889977 . 10.1016/S0065-2911(08)60130-7 . Advances in Microbial Physiology . 978-0-12-027740-7 .