Plasma needling explained

Plasma needling is a minimally invasive aesthetic medical procedure purported to rejuvenate skin, minimize the appearance of hypertrophic and hypotrophic scars and stretchmarks, and reduce pattern hair loss through multimodal physical and biochemical cellular stimulation. It is a combination of classical medical micro-needling by Dermaroller or DermaPen. Both are used in Collagen induction therapy and PRP (platelet-rich plasma). The latter is used in Prolotherapy as well as in the Vampire facelift. The effects on fibroblasts, cells, and micro-needling stem cells are published in scientific publications regarding micro-needling,^{[1] [2] [3]} and the injection of PRP,^{[4] [5] [6] [7]} has also been tested as a combined treatment.^[8]

Notes and References

1. Fabbrocini . G . De Vita . V . Pastore . F . Annunziata . MC . Cacciapuoti . S . Monfrecola . A . Cameli . N . Tosti . A . Apr 2012 . Collagen induction therapy for the treatment of upper lip wrinkles . J. Dermatolog. Treat. . 23 . 2. 144–52 . 10.3109/09546634.2010.544709 . 21810012 . 34680894 .
2. Majid . Imran . Microneedling therapy in atrophic facial scars: An objective assessment . J. Cutan. Aesthet. Surg. . 2009 . 2 . 1 . 26–30 . 10.4103/0974-2077.53096 . 2840919 . 20300368 . free .
3. Liebl . Horst . Kloth . Luther C. . PT . MS . Fapta . CWS . Faccws . 2012 . Skin Cell Proliferation Stimulated by Microneedles . J. Am. Coll. Clin. Wound Spec. . 4 . 1. 2–6 . 10.1016/j.jccw.2012.11.001 . 3921236 . 24527373.
4. Ramos-Torrecillas . J . Luna-Bertos Ed . Manzano-Moreno FJ . García-Martínez . O . Ruiz . C . Mar 2014 . Human fibroblast-like cultures in the presence of platelet-rich plasma as a single growth factor source: clinical implications . Adv. Skin Wound Care . 27 . 3. 114–20 . 10.1097/01.ASW.0000443266.17665.19 . 24531517 . 205385849 .
5. Yuksel . EP . Sahin . G . Aydin . F . Senturk . N . Turanli . AY . Oct 2014 . Evaluation of effects of platelet-rich plasma on human facial skin . J. Cosmet. Laser Ther. . 16 . 5. 206–8 . 10.3109/14764172.2014.949274 . 25065381 . 5908351 .
6. Cervelli . V . Garcovich . S . Bielli . A . Cervelli . G . Curcio . BC . Scioli . MG . Orlandi . A . Gentile . P . 2014 . The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation . Biomed Res. Int. . 2014 . 760709 . 10.1155/2014/760709 . 24883322 . 4032742 . free .
7. Fabi . S . Sundaram . H . Apr 2014 . The potential of topical and injectable growth factors and cytokines for skin rejuvenation . Facial Plast. Surg. . 30 . 2. 157–71 . 10.1055/s-0034-1372423 . 24810127 . free .
8. Nofal . E . Helmy . A . Nofal . A . Alakad . R . Nasr . M . Aug 2014 . Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study . Dermatol. Surg. . 40 . 8. 864–73 . 10.1111/dsu.0000000000000091 . 31 January 2024 . 25006854 .