Pinaverium bromide explained

Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.[1]

Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten[2] and in Argentina as Nulite.[3]

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.[4]

Notes and References

  1. Book: Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines [Internet]. . CADTH Rapid Response Reports . Ottawa (ON) . Canadian Agency for Drugs and Technologies in Health . November 2015 . 26985535 . https://www.ncbi.nlm.nih.gov/books/NBK350043/ .
  2. Web site: Drug/Drug Information: Disten Tablet . KMLE . ko.
  3. Web site: NULITE . Laboratorio Dominguez.
  4. Book: Abbott Laboratories . Dicetel Product Insert/Information Malaysia. Feb 2012 .