Phytoene desaturase (3,4-didehydrolycopene-forming) explained

Phytoene desaturase (3,4-didehydrolycopene-forming)
Ec Number:1.3.99.30

Phytoene desaturase (3,4-didehydrolycopene-forming) (5-step phytoene desaturase, five-step phytoene desaturase, phytoene desaturase (ambiguous), Al-1) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming).[1] [2] This enzyme catalyses the following chemical reaction

15-cis-phytoene + 5 acceptor

\rightleftharpoons

all-trans-3,4-didehydrolycopene + 5 reduced acceptor (overall reaction)

(1a) 15-cis-phytoene + acceptor

\rightleftharpoons

all-trans-phytofluene + reduced acceptor

(1b) all-trans-phytofluene + acceptor

\rightleftharpoons

all-trans-zeta-carotene + reduced acceptor

(1c) all-trans-zeta-carotene + acceptor

\rightleftharpoons

all-trans-neurosporene + reduced acceptor

(1d) all-trans-neurosporene + acceptor

\rightleftharpoons

all-trans-lycopene + reduced acceptor

(1e) all-trans-lycopene + acceptor

\rightleftharpoons

all-trans-3,4-didehydrolycopene + reduced acceptor

This enzyme is involved in carotenoid biosynthesis.

See also

Notes and References

  1. Hausmann A, Sandmann G . A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa . Fungal Genetics and Biology . 30 . 2 . 147–53 . July 2000 . 11017770 . 10.1006/fgbi.2000.1212 .
  2. Estrada AF, Maier D, Scherzinger D, Avalos J, Al-Babili S . Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation . Fungal Genetics and Biology . 45 . 11 . 1497–505 . November 2008 . 18812228 . 10.1016/j.fgb.2008.09.001 .