Phosphomevalonate kinase explained

Phosphomevalonate kinase
Ec Number:2.7.4.2
Cas Number:9026-46-4
Phosphomevalonate kinase
Hgncid:9141
Symbol:PMVK
Entrezgene:10654
Omim:607622
Refseq:NM_006556
Uniprot:Q15126
Ecnumber:2.7.4.2
Chromosome:1
Arm:p
Band:13
Locussupplementarydata:-q23

Phosphomevalonate kinase is an enzyme in the mevalonate pathway[1] [2] [3] that in humans is encoded by the PMVK gene.

Notes and References

  1. Bloch K, Chaykin S, Phillips AH, De Waard A . Mevalonic acid pyrophosphate and isopentenylpyrophosphate . The Journal of Biological Chemistry . 234 . 2595–604 . October 1959 . 10 . 10.1016/S0021-9258(18)69744-3 . 13801508 . free .
  2. Henning U, Moslein EM, Lynen F . Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase . Archives of Biochemistry and Biophysics . 83 . 1 . 259–67 . July 1959 . 13662013 . 10.1016/0003-9861(59)90031-1 .
  3. Levy HR, Popjak G . Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver . The Biochemical Journal . 75 . 417–28 . June 1960 . 3 . 14416398 . 1204488 . 10.1042/bj0750417 .