Phosphoamidase Explained
phosphoamidase |
Ec Number: | 3.9.1.1 |
Cas Number: | 9001-79-0 |
Go Code: | 0050187 |
In enzymology, a phosphoamidase is an enzyme that catalyzes the chemical reaction
N-phosphocreatine + H2O
creatine + phosphate
Thus, the two substrates of this enzyme are N-phosphocreatine and H2O, whereas its two products are creatine and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphorus-nitrogen bonds. The systematic name of this enzyme class is phosphamide hydrolase. This enzyme is also called creatine phosphatase.
References
- Parvin R, Smith RA . 1969 . Phosphoramidates. V. Probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase . Biochemistry . 8 . 1748 - 55 . 4308726 . 10.1021/bi00832a058 . 4 .
- Singer MF . Fruton JS . 1957 . Some properties of beef spleen phosphoamidase . J. Biol. Chem. . 229 . 111 - 119 . 13491564 . 1. 10.1016/S0021-9258(18)70599-1 . free .
- Sundarajan TA . Sarma PS . 1959 . Substrate specificity of phosphoprotein phosphatase from spleen . Biochem. J. . 71 . 3 . 537 - 544 . 10.1042/bj0710537 . 13638262 . 1196829 .