| phenylglyoxylate dehydrogenase (acylating) | |
| Ec Number: | 1.2.1.58 |
| Cas Number: | 205510-78-7 |
| Go Code: | 0047110 |
In enzymology, a phenylglyoxylate dehydrogenase (acylating;) is an enzyme that catalyzes the chemical reaction
phenylglyoxylate + NAD+ + CoA-SH
\rightleftharpoons
The three substrates of this enzyme are phenylglyoxylate, NAD+, and CoA-SH, whereas its 3 products are benzoyl-S-CoA, CO2, and NADH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is phenylglyoxylate:NAD+ oxidoreductase. It has 3 cofactors: FAD, Thiamin diphosphate, and Iron-sulfur.