Pegylated interferon explained

Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012:[1]

In these formulations, Polyethylene glycol (PEG) is added to make interferon last longer in the body.[3] They are used to treat both hepatitis B,[4] hepatitis C[1] and multiple sclerosis.

Pegylated interferon is contraindicated in patients with hyperbilirubinaemia.

Notes and References

  1. Book: editor, Emilio Jirillo. Hepatitis C virus disease : immunobiology and clinical applications. 2008. Springer. New York. 978-0-387-71375-5. 237. [Online-Ausg.].
  2. Kieseier BC, Calabresi PA. . PEGylation of Interferon-β-1a: A Promising Strategy in Multiple Sclerosis . https://archive.today/20130101231543/http://adisonline.com/cnsdrugs/Abstract/2012/26030/PEGylation_of_Interferon___1a__A_Promising.2.aspx . dead . 2013-01-01 . CNS Drugs . 26 . 3 . 205–14 . 2012 . 10.2165/11596970-000000000-00000 . 22201341 . Calabresi . 34290702 .
  3. Web site: Hepatology Focus: Update on Hepatitis C Treatment: Pegylated Interferon. Martin P. February 15, 2001. medscape.
  4. Book: Dancygier H, Allescher HD. Clinical Hepatology. 2010. Springer Berlin Heidelberg. [S.l.]. 978-3-642-04509-7. 765.

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