Parkeol synthase explained

Parkeol synthase
Ec Number:	5.4.99.47

Parkeol synthase is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, parkeol-forming).^[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene

\rightleftharpoons parkeol

The enzyme from rice (Oryza sativa) produces only parkeol.

Notes and References

1. Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T . Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases . Organic Letters . 13 . 10 . 2678–81 . May 2011 . 21526825 . 10.1021/ol200777d .