Pantoate kinase explained

Pantoate kinase
Ec Number:	2.7.1.169

Pantoate kinase (PoK, TK2141 protein) is an enzyme with systematic name ATP:(R)-pantoate 4-phosphotransferase.^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons ADP + (R)-4-phosphopantoate

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is done during biosynthesis of 4'-phosphopantetheine,.

Notes and References

1. Yokooji Y, Tomita H, Atomi H, Imanaka T . Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea . The Journal of Biological Chemistry . 284 . 41 . 28137–45 . October 2009 . 19666462 . 2788864 . 10.1074/jbc.m109.009696 . free .