Pancreatic elastase II explained

Pancreatic elastase II
Ec Number:3.4.21.71
Cas Number:75603-19-9

Pancreatic elastase II (pancreatic elastase 2) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Preferential cleavage: Leu-, Met- and Phe-. Hydrolyses elastin

This peptidase from trypsin family is formed by activation of proelastase II from mammalian pancreas by trypsin.

Notes and References

  1. Fletcher TS, Shen WF, Largman C . Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA . Biochemistry . 26 . 23 . 7256–61 . November 1987 . 3427074 . 10.1021/bi00397a010 .
  2. Shirasu Y, Yoshida H, Matsuki S, Takemura K, Ikeda N, Shimada Y, Ozawa T, Mikayama T, Iijima H, Ishida A . Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2 . Journal of Biochemistry . 102 . 6 . 1555–63 . December 1987 . 2834346 . 10.1093/oxfordjournals.jbchem.a122204 .