PLDN explained

Pallidin is a protein that in humans is encoded by the PLDN gene.[1] [2]

Function

The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Interactions

PLDN has been shown to interact with:

Further reading

Notes and References

  1. Huang L, Kuo YM, Gitschier J . The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency . Nat Genet . 23 . 3 . 329–32 . Dec 1999 . 10610180 . 10.1038/15507 . 22843205 .
  2. Web site: Entrez Gene: PLDN pallidin homolog (mouse).
  3. Starcevic M, Dell'Angelica EC . Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1) . J. Biol. Chem. . 279 . 27 . 28393–401 . Jul 2004 . 15102850 . 10.1074/jbc.M402513200 . free .
  4. Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC . BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules . J. Biol. Chem. . 277 . 31 . 28191–9 . Aug 2002 . 12019270 . 10.1074/jbc.M204011200 . free .