Oxoeicosanoid Explained

The oxoeicosanoids are nonclassic eicosanoids, derived from arachidonic acid (AA).For example, Lipoxygenase produces 5-HETE from AA; a dehydrogenase then produces 5-oxo-eicosatetraenoic acid, an oxoeicosanoid, from 5-HETE. They are similar to the leukotrienes in their actions, but they act via a different receptor.[1]

References

  1. Powell WS, Chung D, Gravel S . 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration . J. Immunol. . 154 . 8 . 4123–32 . 1995 . 10.4049/jimmunol.154.8.4123 . 7706749 .