Oxiperomide Explained

Oxiperomide is an antipsychotic.[1] Clinical trials demonstrated that it can reduce dyskinesia in patients with Parkinson's disease who are taking dopamine agonists without increasing Parkinsonian symptoms. It does this by selectively antagonizing dopamine receptors.[2] [3] Further development of this drug is not available. It appears to have never been marketed.

See also

Notes and References

  1. Book: The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Elks J . 1990 . Springer . 978-1-4757-2085-3 . Dordrecht . Oxiperomide . https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA916.
  2. Bédard P, Parkes JD, Marsden CD . April 1978 . Effect of new dopamine-blocking agent (oxiperomide) on drug-induced dyskinesias in Parkinson's disease and spontaneous dyskinesias . British Medical Journal . 1 . 6118 . 954–956 . 10.1136/bmj.1.6118.954 . 638546. 1603806 .
  3. Casey DE, Gerlach J . March 1980 . Oxiperomide in tardive dyskinesia . Journal of Neurology, Neurosurgery, and Psychiatry . 43 . 3 . 264–267 . 10.1136/jnnp.43.3.264 . 7373324. 490519 .

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