Oxidized cellulose explained

Oxidized cellulose is a water-insoluble derivative of cellulose. It can be produced from cellulose by the action of an oxidizing agent, such as chlorine, hydrogen peroxide, peracetic acid, chlorine dioxide, nitrogen dioxide, persulfates, permanganate, dichromate-sulfuric acid, hypochlorous acid, hypohalites or periodates and a variety of metal catalysts.[1] Oxidized cellulose may contain carboxylic acid, aldehyde, and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose, depending on the nature of the oxidant and reaction conditions.[2]

It is an antihemorrhagic.[3] It works both by absorbing the blood (similar to a cotton ball)[4] and by triggering the contact activation system. It is poorly absorbed and may cause healing complications postoperatively.[5]

See also

Notes and References

  1. Collinson SR, Thielemans W . The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin. . Coordination Chemistry Reviews . August 2010 . 254 . 15–16 . 1854–1870 . 10.1016/j.ccr.2010.04.007 .
  2. US . 5780618 . Oxidized cellulose . Banker GS, Kumar V . Biocontrol Inc.. 14 July 1998 .
  3. Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS . MR characteristics of oxidized cellulose (Surgicel) . AJR. American Journal of Roentgenology . 172 . 6 . 1481–1484 . June 1999 . 10350276 . 10.2214/ajr.172.6.10350276 . free .
  4. Web site: Oxidised Cellulose . Advanced Medical Solutions Group plc. 30 November 2023 .
  5. Book: Resnik RR . Intraoperative Complications . Resnik RR, Misch CE . Misch's Avoiding Complications in Oral Implantology . 2018 . 267–293 . 10.1016/B978-0-323-37580-1.00007-X. 978-0-323-37580-1 .

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