| orotate reductase (NADPH) | |
| Ec Number: | 1.3.1.15 |
| Cas Number: | 37255-27-9 |
| Go Code: | 0050158 |
In enzymology, an orotate reductase (NADPH) is an enzyme that catalyzes the chemical reaction
(S)-dihydroorotate + NADP+
\rightleftharpoons
Thus, the two substrates of this enzyme are (S)-dihydroorotate and NADP+, whereas its 3 products are orotate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-dihydroorotate:NADP+ oxidoreductase. Other names in common use include orotate reductase, dihydroorotate dehydrogenase, dihydro-orotic dehydrogenase, L-5,6-dihydro-orotate:NAD+ oxidoreductase, and orotate reductase (NADPH). It has one cofactor, FAD.