Optic vesicle explained

Optic vesicle
Latin:	vesicula optica; vesicula ophthalmica
Carnegiestage:	11
Givesriseto:	Human eyes

The eyes begin to develop as a pair of diverticula (pouches) from the lateral aspects of the forebrain. These diverticula make their appearance before the closure of the anterior end of the neural tube;^{[1] [2]} after the closure of the tube around the 4th week of development, they are known as the optic vesicles. Previous studies of optic vesicles suggest that the surrounding extraocular tissues – the surface ectoderm and extraocular mesenchyme – are necessary for normal eye growth and differentiation.^[3]

They project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk, which goes on to form the optic nerve.^{[4] [5]}

See also

• Eye development

References

Sources

• Fuhrmann, S. (2010). Eye Morphogenesis and Patterning of the Optic Vesicle. Current Topics in Developmental Biology Invertebrate and Vertebrate Eye Development, 61–84. doi:10.1016/b978-0-12-385044-7.00003-5

External links

• • Overview at vision.ca
• Overview at temple.edu

Notes and References

1. Hosseini . Hadi S. . Beebe . David C. . Taber . Larry A.. Mechanical Effects of the Surface Ectoderm on Optic Vesicle Morphogenesis in the Chick Embryo . Journal of Biomechanics . 2014 . 47 . 16 . 3837–3846 . 10.1016/j.jbiomech.2014.10.018 . 25458577 . 4261019 .
2. Hosseini . Hadi S. . Taber . Larry A. . How mechanical forces shape the developing eye . Progress in Biophysics and Molecular Biology . 2018 . 137 . 16 . 25–36 . 10.1016/j.pbiomolbio.2018.01.004. 29432780 . 6085168 .
3. Fuhrmann, S. (2010). Eye Morphogenesis and Patterning of the Optic Vesicle. Current Topics in Developmental Biology Invertebrate and Vertebrate Eye Development, 61-84. doi:10.1016/b978-0-12-385044-7.00003-5
4. Hosseini . Hadi S. . Beebe . David C. . Taber . Larry A. . Mechanical effects of the surface ectoderm on optic vesicle morphogenesis in the chick embryo . Journal of Biomechanics . 2014 . 47 . 16 . 3837–3846 . 10.1016/j.jbiomech.2014.10.018 . 25458577 . 4261019 .
5. Hosseini . Hadi S. . Taber . Larry A. . How mechanical forces shape the developing eye . Progress in Biophysics and Molecular Biology . 2018 . 137 . 16 . 25–36 . 10.1016/j.pbiomolbio.2018.01.004. 29432780 . 6085168 .