Oleoyl-(acyl-carrier-protein) hydrolase explained

acyl-ACP thioesterase
Ec Number:	3.1.2.14
Cas Number:	68009-83-6
Go Code:	0010281

The enzyme oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) catalyzes the reaction

an oleoyl-[acyl-carrier-protein] + H₂O

\rightleftharpoons an [acyl-carrier-protein] + oleate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. It participates in fatty acid biosynthesis.

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

References

• Ohlrogge JB, Shine WE, Stumpf PK . 1978 . Fat metabolism in higher plants. Characterization of plant acyl-ACP and acyl-CoA hydrolases . Arch. Biochem. Biophys. . 189 . 382 - 91 . 30409 . 10.1016/0003-9861(78)90225-4 . 2 .
• Shine WE, Mancha M, Stumpf PK . 1976 . Fat metabolism in higher plants. The function of acyl thioesterases in the metabolism of acyl-coenzymes A and acyl-acyl carrier proteins . Arch. Biochem. Biophys. . 172 . 110 - 6 . 3134 . 10.1016/0003-9861(76)90054-0 . 1 .