| nucleoside deoxyribosyltransferase | |
| Ec Number: | 2.4.2.6 |
| Cas Number: | 9026-86-2 |
| Go Code: | 0050144 |
| Width: | 270 |
In enzymology, a nucleoside deoxyribosyltransferase is an enzyme that catalyzes the chemical reaction
2-deoxy-D-ribosyl-base1 + base2
\rightleftharpoons
Thus, the two substrates of this enzyme are 2-deoxy-D-ribosyl-base1 and base2, whereas its two products are 2-deoxy-D-ribosyl-base2 and base1.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase. Other names in common use include purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl, transferase, deoxyribose transferase, nucleoside trans-N-deoxyribosylase, trans-deoxyribosylase, trans-N-deoxyribosylase, trans-N-glycosidase, nucleoside deoxyribosyltransferase I (purine nucleoside:purine, deoxyribosyltransferase: strictly specific for transfer between, purine bases), nucleoside deoxyribosyltransferase II [purine(pyrimidine)''', and '''nucleoside:purine(pyrimidine) deoxyribosyltransferase]. This enzyme participates in pyrimidine metabolism.
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,,,,, and .