Nothoapiole Explained

Nothoapiole is a phenylpropene, a natural organic compound present in the essential oil of Perilla frutescens from Jeju Island in Korea^[1] and the major component of the essential oil obtained from the roots of Pleurospermum angelicoides Benth.^[2] It is also found in the essential oil of black caraway (Carum bulbocastanum) fruits^[3] and Carum nigrum.^[4]

This highly oxygenated phenylpropanoid, previously reported in a few Carum species, is structurally and biogenetically related to myristicin, apiole and dillapiole.^{[5] [6]}

See also

• Elemicin
• Myristicin
• Apiole
• Dillapiole

Notes and References

1. 10.1248/bpb.22.598. Genetic Analysis of Nothoapiol Formation in Perilla frutescens. Biological & Pharmaceutical Bulletin. 22. 6. 598–601. 1999. Ito. Michiho. Toyoda. Mariko. Yuba. Akiko. Honda. Gisho. 10408233. free.
2. http://www.acgpubs.org/RNP/2015/Volume9/Issue%201/67-RNP-EO_1202-015.pdf
3. Journal of the Science of Food and Agriculture Volume 90, Issue 3, pages 385–390, February 2010
4. 10.1021/jf0518610. 16390196. Antioxidant and Biocidal Activities of Carum nigrum(Seed) Essential Oil, Oleoresin, and Their Selected Components†. Journal of Agricultural and Food Chemistry. 54. 1. 174–81. 2006. Singh. Gurdip. Marimuthu. Palanisamy. De Heluani. Carola S.. Catalan. Cesar A. N.. 11336/99544. free.
5. H. Laouer . E.K. Meriem . S. Prado . N. Baldovini . 2009 . An antibacterial and antifungal phenylpropanoid from Carum montanum (Coss. et Dur.) Benth. et Hook . Phytother. Res. . 23 . 12 . 1726–1730. 19370550 . 10.1002/ptr.2820 . 2668369 .
6. M. Ito . M. Toyoda . A. Yuba . G. Honda . 1999 . Genetic analysis of nothoapiole formation in Perilla frutescens . Biol. Pharm. Bull. . 22 . 6 . 598–601. 10408233 . 10.1248/bpb.22.598. free .