Normustine Explained

Normustine, also known as bis(2-chloroethyl)carbamic acid, is a nitrogen mustard and alkylating antineoplastic agent (i.e., chemotherapy agent).[1] [2] [3] It is a metabolite of a number of antineoplastic agents that have been developed for the treatment of tumors, including estramustine phosphate, alestramustine, cytestrol acetate, and ICI-85966 (stilbostat), but only the former of which has actually been marketed.

Notes and References

  1. Book: Brunton L, Chabner B, Knollman B . Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition. 14 January 2011. McGraw Hill Professional. 978-0-07-176939-6. 1709.
  2. Book: Fox BW, Fox M . Antitumor Drug Resistance. 6 December 2012. Springer Science & Business Media. 978-3-642-69490-5. 199–.
  3. Book: Decker M . Design of Hybrid Molecules for Drug Development. 5 April 2017. Elsevier Science. 978-0-08-101118-8. 201–.

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