Nitric oxide reductase (menaquinol) explained

Nitric oxide reductase (menaquinol)
Ec Number:	1.7.5.2

Nitric oxide reductase (menaquinol) is an enzyme.^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

\rightleftharpoons nitrous oxide + menaquinone + H₂O

Nitric oxide reductase contains copper.

In 2015 the laboratory that had characterized the Bacillus azotoformans enzyme wrote, "The copper-A-dependent Nor from Bacillus azotoformans uses cytochrome c₅₅₁ as electron donor but lacks menaquinol activity, in contrast to our earlier report."^[4]

Notes and References

1. Cramm R, Pohlmann A, Friedrich B . Purification and characterization of the single-component nitric oxide reductase from Ralstonia eutropha H16 . FEBS Letters . 460 . 1 . 6–10 . October 1999 . 10571051 . 10.1016/s0014-5793(99)01315-0 .
2. Strampraad MJ, Schröder I, de Vries S . A novel copper A containing menaquinol NO reductase from Bacillus azotoformans . Biochemistry . 40 . 8 . 2632–9 . February 2001 . 11327887 . 10.1021/bi0020067 .
3. Heering HA, de Vries S . NO reductase from Bacillus azotoformans is a bifunctional enzyme accepting electrons from menaquinol and a specific endogenous membrane-bound cytochrome c551 . Biochemistry . 43 . 42 . 13487–95 . October 2004 . 15491156 . 10.1021/bi0488101 .
4. Al-Attar S, de Vries S . An electrogenic nitric oxide reductase . FEBS Letters . 589 . 16 . 2050–7 . July 2015 . 26149211 . 10.1016/j.febslet.2015.06.033 .