Nitrate reductase (NADPH) explained

Nitrate reductase (NADPH)
Ec Number:1.7.1.3
Cas Number:9029-28-1

Nitrate reductase (NADPH) (assimilatory nitrate reductase, assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase, NADPH-nitrate reductase, assimilatory NADPH-nitrate reductase, triphosphopyridine nucleotide-nitrate reductase, NADPH:nitrate reductase, nitrate reductase (NADPH2), NADPH2:nitrate oxidoreductase) is an enzyme with systematic name nitrite:NADP+ oxidoreductase.[1] [2] [3] [4] This enzyme catalises the following chemical reaction

nitrite + NADP+ + H2O

\rightleftharpoons

nitrate + NADPH + H+

Nitrate reductase is an iron-sulfur molybdenum flavoprotein.

Notes and References

  1. Book: Nitrate reductases . The Enzymes . Nason A . 1963 . 7 . 587–607 . Boyer PD, Lardy H, Myrbäck K . 2nd . Academic Press . New York .
  2. Nason A, Evans HJ . Triphosphopyridine nucleotide-nitrate reductase in Neurospora . The Journal of Biological Chemistry . 202 . 2 . 655–73 . June 1953 . 13061490 .
  3. Nicholas DJ, Nason A . Molybdenum and nitrate reductase. II. Molybdenum as a constituent of nitrate reductase . The Journal of Biological Chemistry . 207 . 1 . 353–60 . March 1954 . 13152110 .
  4. Berks BC, Ferguson SJ, Moir JW, Richardson DJ . Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions . Biochimica et Biophysica Acta (BBA) - Bioenergetics . 1232 . 3 . 97–173 . December 1995 . 8534676 . 10.1016/0005-2728(95)00092-5 . free .