Nitrate reductase (NAD(P)H) explained

Nitrate reductase (NAD(P)H)
Ec Number:	1.7.1.2
Cas Number:	9029-27-0

Nitrate reductase (NAD(P)H) (assimilatory nitrate reductase, assimilatory NAD(P)H-nitrate reductase, NAD(P)H bispecific nitrate reductase, nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)), nitrate reductase NAD(P)H, NAD(P)H-nitrate reductase, nitrate reductase [NAD(P)H₂], NAD(P)H₂:nitrate oxidoreductase) is an enzyme with systematic name nitrite:NAD(P)⁺ oxidoreductase.^{[1] [2] [3] [4]} This enzyme catalises the following chemical reaction

nitrite + NAD(P)⁺ + H₂O

\rightleftharpoons nitrate + NAD(P)H + H⁺

Nitrate reductase is an iron-sulfur molybdenum flavoprotein.

Notes and References

1. Book: Nitrate reductases . The Enzymes . Nason, A. . 1963 . 7 . 587–607 . Boyer, P.D. . Lardy, H. . Myrbäck, K. . 2nd . Academic Press . New York .
2. Paneque A, Del Campo FF, Ramírez JM, Losada M . Flavin nucleotide nitrate reductase from spinach . Biochimica et Biophysica Acta (BBA) - Biophysics Including Photosynthesis . 109 . 1 . 79–85 . September 1965 . 5864033 . 10.1016/0926-6585(65)90092-0 .
3. Campbell WH . Structure and function of eukaryotic NAD(P)H:nitrate reductase . Cellular and Molecular Life Sciences . 58 . 2 . 194–204 . February 2001 . 11289301 . 10.1007/pl00000847 . 11146515 .
4. Berks BC, Ferguson SJ, Moir JW, Richardson DJ . Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions . Biochimica et Biophysica Acta (BBA) - Bioenergetics . 1232 . 3 . 97–173 . December 1995 . 8534676 . 10.1016/0005-2728(95)00092-5 . free .