Nitecapone Explained

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1] [2] It was patented as an antiparkinson medication but was never marketed.

See also

Notes and References

  1. Book: F.. Macdonald . Dictionary of Pharmacological Agents . 20 May 2012 . 1997 . CRC Press . 978-0-412-46630-4 . 1635.
  2. Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P . Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat . European Journal of Pharmacology . 153 . 2–3 . 263–9 . August 1988 . 3181288 . 10.1016/0014-2999(88)90614-0.

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