Nifenazone Explained

Nifenazone is a drug that has been used as an analgesic for a number of rheumatic conditions.^[1]

Synthesis

Nifenazone is the amide formed when ampyrone and the acid chloride of nicotinic acid are combined in a Schotten–Baumann reaction.^{[2] [3]}

See also

• Aminopyrine

Notes and References

1. Hart FD, Boardman PL . British Medical Journal . 1 . 5397 . 1553–4 . June 1964 . 14133613 . 1814611 . 10.1136/bmj.1.5397.1553 . Trial of Nifenazone ("Thylin") .
2. 10.1007/BF00901766 . Über neue pharmakologisch wirksame Amide und Ester der Nicotinsäure . 1957 . Pongratz A, Zirm L . Monatshefte für Chemie . 88 . 3 . 330–335 .
3. Web site: Nifenazone . Pharmaceutical Substances . Georg Thieme Verlag KG . 2024-07-16 .