| Nicotinate phosphoribosyltransferase | |
| Ec Number: | 6.3.4.21 |
| Cas Number: | 9030-26-6 |
| Go Code: | 0004516 |
| Width: | 270 |
In enzymology, a nicotinate phosphoribosyltransferase is an enzyme that catalyzes the chemical reaction
nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O
\rightleftharpoons
Thus, the four substrates of this enzyme are nicotinate, 5-phospho-alpha-D-ribose 1-diphosphate, ATP, and H2O, whereas its four products are nicotinate D-ribonucleotide, diphosphate, ADP, and phosphate.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is 5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming) .
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and .