| nicotinate N-methyltransferase | |
| Ec Number: | 2.1.1.7 |
| Cas Number: | 9029-79-2 |
| Go Code: | 0008938 |
| Width: | 270 |
In enzymology, a nicotinate N-methyltransferase is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + nicotinate
\rightleftharpoons
Thus, the two substrates of this enzyme are S-adenosyl methionine and nicotinate, whereas its two products are S-adenosylhomocysteine and N-methylnicotinate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:nicotinate N-methyltransferase. Other names in common use include furanocoumarin 8-methyltransferase, and furanocoumarin 8-O-methyltransferase. This enzyme participates in nicotinate and nicotinamide metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .