| nicotinate-nucleotide adenylyltransferase | |
| Ec Number: | 2.7.7.18 |
| Cas Number: | 9026-98-6 |
| Go Code: | 0004515 |
In enzymology, a nicotinate-nucleotide adenylyltransferase is an enzyme that catalyzes the chemical reaction
ATP + nicotinate ribonucleotide
\rightleftharpoons
Thus, the two substrates of this enzyme are ATP and nicotinate ribonucleotide, whereas its two products are diphosphate and deamido-NAD+.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:nicotinate-ribonucleotide adenylyltransferase. Other names in common use include deamido-NAD+ pyrophosphorylase, nicotinate mononucleotide adenylyltransferase, deamidonicotinamide adenine dinucleotide pyrophosphorylase, NaMN-ATase, and nicotinic acid mononucleotide adenylyltransferase. This enzyme participates in nicotinate and nicotinamide metabolism.
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,, and .