Nevus cell explained

Nevus cells are a variant of melanocytes.^[1] They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules.^[2] They are usually located at the dermoepidermal junction or in the dermis of the skin. Dermal nevus cells can be further classified: type A (epithelioid) dermal nevus cells mature into type B (lymphocytoid) dermal nevus cells which mature further into type C (neuroid) dermal nevus cells, through a process involving downwards migration.

Nevus cells are the primary component of a melanocytic nevus.

Nevus cells can also be found in lymph nodes^[3] and the thymus.^[4]

See also

• List of human cell types derived from the germ layers

Notes and References

1. Book: James, William D. . Berger, Timothy G. . Andrews' Diseases of the Skin: clinical Dermatology . Saunders Elsevier . 2006 . 978-0-7216-2921-6 . etal.
2. Book: Habif, Thomas P. . Clinical Dermatology, 5th ed. . 2010 . Mosby . 978-0-7234-3541-9 . 847.
3. Biddle DA, Evans HL, Kemp BL, etal . Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma . Am. J. Surg. Pathol. . 27 . 5 . 673–81 . May 2003 . 12717252 . 10.1097/00000478-200305000-00011. 19802372 .
4. Parker JR, Ro JY, Ordóñez NG . Benign nevus cell aggregates in the thymus: a case report . Mod. Pathol. . 12 . 3 . 329–32 . March 1999 . 10102620 .