Neuromedin U receptor 2 explained

Neuromedin-U receptor 2 is a protein that in humans is encoded by the NMUR2 gene.^{[1] [2] [3]}

Ligands

Agonists

• synephrine^[4]

See also

• Neuromedin U receptor

Further reading

• Hosoya M, Moriya T, Kawamata Y, etal . Identification and functional characterization of a novel subtype of neuromedin U receptor. . J. Biol. Chem. . 275 . 38 . 29528–32 . 2000 . 10887190 . 10.1074/jbc.M004261200 . free .
• Raddatz R, Wilson AE, Artymyshyn R, etal . Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. . J. Biol. Chem. . 275 . 42 . 32452–9 . 2000 . 10899166 . 10.1074/jbc.M004613200 . free .
• Shan L, Qiao X, Crona JH, etal . Identification of a novel neuromedin U receptor subtype expressed in the central nervous system. . J. Biol. Chem. . 275 . 50 . 39482–6 . 2001 . 11010960 . 10.1074/jbc.C000522200 . free .
• Fernández Alvarez C, Debeljuk L, Díaz Rodríguez E, Díaz López B . Developmental pattern of tachykinins during aging in several organs: effect of exogenous melatonin. . Peptides . 23 . 9 . 1617–23 . 2003 . 12217422 . 10.1016/S0196-9781(02)00099-2 . 9986371 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Bhattacharyya S, Luan J, Farooqi IS, etal . Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor. . J. Endocrinol. . 183 . 1 . 115–20 . 2004 . 15525579 . 10.1677/joe.1.05830 . free .
• Mori K, Miyazato M, Ida T, etal . Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. . EMBO J. . 24 . 2 . 325–35 . 2005 . 15635449 . 10.1038/sj.emboj.7600526 . 545815 .
• Fang L, Zhang M, Li C, etal . Chemical genetic analysis reveals the effects of NMU2R on the expression of peptide hormones. . Neurosci. Lett. . 404 . 1–2 . 148–53 . 2006 . 16781063 . 10.1016/j.neulet.2006.05.034 . 26500367 .

External links

• Web site: Neuromedin U Receptors: NMU2 . IUPHAR Database of Receptors and Ion Channels . International Union of Basic and Clinical Pharmacology . 2008-12-05 . 2016-03-03 . https://web.archive.org/web/20160303201503/http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2899 . dead .

Notes and References

1. Tate CG, Grisshammer R . Heterologous expression of G-protein-coupled receptors . Trends Biotechnol . 14 . 11 . 426–30 . Jan 1997 . 8940772 . 10.1016/0167-7799(96)10059-7 .
2. Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, ((Williams DL Jr)), Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q . Identification of receptors for neuromedin U and its role in feeding . Nature . 406 . 6791 . 70–4 . Jul 2000 . 10894543 . 10.1038/35017610 . 205007370 .
3. Web site: Entrez Gene: NMUR2 neuromedin U receptor 2.
4. Biol Pharm Bull. 24598981. 37. 5. p-Synephrine: a novel agonist for neuromedin U2 receptor. 2014. 764–70. Zheng X, Guo L, Wang D, Deng X. 10.1248/bpb.b13-00788. free.