Mycosamine Explained

D-Mycosamine is an amino sugar found in several polyene antimycotics. Structural analogs of these agents lacking this monosaccharide component do not exhibit substantial antifungal activity.^[1]

References

• Biosynthesis: https://biocyc.org/META/NEW-IMAGE?object=PWY-7573

Notes and References

1. Analysis of the Mycosamine Biosynthesis and Attachment Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 . A. . Nedal . H. . Sletta . T. . Brautaset . S. E. F. . Borgos . O. N. . Sekurova . T. E. . Ellingsen . S. B. . Zotchev . 17 December 2020 . Applied and Environmental Microbiology . 73 . 22 . 7400–7407 . 10.1128/AEM.01122-07 . 17905880 . 2168226 .