Mycoredoxin Explained

Mycoredoxin
Ec Number:	1.20.4.3

Mycoredoxin (Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

arseno-mycothiol + mycoredoxin

\rightleftharpoons

arsenite + mycothiol-mycoredoxin disulfide

Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.

Notes and References

Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J . Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange . The Journal of Biological Chemistry . 284 . 22 . 15107–16 . May 2009 . 19286650 . 2685692 . 10.1074/jbc.m900877200 . free .