Mucinaminylserine mucinaminidase explained

mucinaminylserine mucinaminidase
Ec Number:	3.2.1.110
Cas Number:	59793-96-3
Go Code:	0050110

In enzymology, a mucinaminylserine mucinaminidase is an enzyme that catalyzes the chemical reaction

D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H₂O

\rightleftharpoons D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine

Thus, the two substrates of this enzyme are D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine and H₂O, whereas its two products are D-galactosyl-3-N-acetyl-beta-D-galactosamine and L-serine.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase. Other names in common use include endo-alpha-N-acetylgalactosaminidase, and endo-alpha-N-acetyl-D-galactosaminidase.

References

• Bhavanandan VP, Umemoto J, Davidson EA . 1976 . Characterization of an endo-alpha-N-acetyl galactosaminidase from Diplococcus pneumoniae . Biochem. Biophys. Res. Commun. . 70 . 738 - 45 . 7253 . 10.1016/0006-291X(76)90654-9 . 3 .
• Endo Y, Kobata A . Tokyo . Partial purification and characterization of an endo-alpha-N-acetylgalactosaminidase from the culture of medium of Diplococcus pneumoniae . J. Biochem. . 80. 1 - 8 . 9374 . 1 . July 1976 . 10.1093/oxfordjournals.jbchem.a131240.
• Umemoto J, Bhavanandan VP, Davidson EA . 1977 . Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae . J. Biol. Chem. . 252 . 8609 - 14 . 21877 . 23 .