Morin (flavonol) explained

Morin is a yellow chemical compound that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic), and from leaves of Psidium guajava (common guava).^[1] In a preclinical in vitro study, morin was found to be a weak inhibitor of fatty acid synthase with an IC₅₀ of 2.33 μM.^[2] Morin was also found to inhibit amyloid formation by islet amyloid polypeptide (or amylin) and disaggregate amyloid fibers.^[3]

Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them under UV light.

Glycosides

• Morin-3-O-arabinoside
• Morin-3-O-lyxoside^[1]

Notes and References

1. 10.1016/j.fitote.2007.03.015 . Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens . Fitoterapia . 78 . 6 . 434–436 . 2007 . Rattanachaikunsopon . Pongsak . Phumkhachorn . Parichat . 17553634 .
2. 10.2174/092986706776361012 . Inhibition of Fatty Acid Synthase by Polyphenols . Current Medicinal Chemistry . 13 . 8 . 967–977 . 2006 . Tian . Wei-Xi . 16611078 .
3. 10.1002/pro.2023. 3375438. Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers. Protein Science. 21. 3. 373–382. 2012. Noor. Harris. Cao. Ping. Raleigh. Daniel P.. 22238175.