Mizolastine Explained

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Watchedfields:changed
Verifiedrevid:449584902
Iupac Name:2-[{1-[1-(4-Fluorobenzyl)-1''H''-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one
Legal Uk:POM
Routes Of Administration:By mouth (tablets)
Cas Number:108612-45-9
Atc Prefix:R06
Atc Suffix:AX25
Pubchem:65906
Unii:244O1F90NA
Kegg:D01117
Chembl:94454
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Mizolastine (Mizollen) is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting.[1] It does not prevent the actual release of histamine from mast cells, it only prevents histamine from binding to receptors. Side effects can include dry mouth and throat.[2]

Notes and References

  1. Simons FE . Mizolastine: antihistaminic activity from preclinical data to clinical evaluation . Clinical and Experimental Allergy . 29 . Suppl 1. 3–8 . March 1999 . 10209699 . 10.1046/j.1365-2222.1999.00002.x. 616333 .
  2. Web site: MIZOLASTINE: British National Formulary. 2010-02-01.