Micropolygyria Explained

Synonyms:	Polymicrogyria, Polygyria, or Microgyria
Field:	neurology

Micropolygyria is a neuronal migration disorder, a developmental anomaly of the brain characterized by development of numerous small convolutions (microgyri), causing intellectual disability and/or other neurological disorders.^[1] It is present in a number of specific neurological diseases, notably multiple sclerosis and, a specific disease cause by mutation in the gene (FKTN).^{[2] [3]}

See also

• Glia limitans

Notes and References

1. Dorland's Illustrated Medical Dictionary Merck .
2. 17036286 . 10.1002/ana.20973 . 60 . 5 . Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness . November 2006 . Murakami T, Hayashi YK, Noguchi S, etal . Ann. Neurol. . 597–602. free .
3. 11592034 . 10.1086/324412 . 69 . 6 . Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin alpha2 deficiency and abnormal glycosylation of alpha-dystroglycan . 1235559 . December 2001 . Brockington M, Blake DJ, Prandini P, etal . Am. J. Hum. Genet. . 1198–209.