Metomidate Explained

Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965^[1] and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.^[2]

¹¹C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.^{[3] [4]}

See also

• Etomidate
• Propoxate

Notes and References

1. BE Patent 662474
2. Book: Index nominum 2000: international drug directory . 27 October 2011 . 2000 . Taylor & Francis US . 978-3-88763-075-1 . 683.
3. Khan TS, Sundin A, Juhlin C, Långström B, Bergström M, Eriksson B . 11C-metomidate PET imaging of adrenocortical cancer . European Journal of Nuclear Medicine and Molecular Imaging . 30 . 3 . 403–10 . March 2003 . 12634969 . 10.1007/s00259-002-1025-9 . 23744095 .
4. Minn H, Salonen A, Friberg J, Roivainen A, Viljanen T, Långsjö J, Salmi J, Välimäki M, Någren K, Nuutila P . 6 . Imaging of adrenal incidentalomas with PET using (11)C-metomidate and (18)F-FDG . Journal of Nuclear Medicine . 45 . 6 . 972–9 . June 2004 . 15181132 .