Metodesnitazene Explained

Metodesnitazene (also known as Metazene) is a benzimidazole derivative with opioid effects, though unlike related compounds such as metonitazene and etodesnitazene which are quite potent, metodesnitazene is only around the same potency as morphine in animal studies.[1] [2] [3] [4] [5] It is illegal in both the US and UK.

See also

Notes and References

  1. Hunger A, Kebrle J, Rossi A, Hoffmann K . Benzimidazol-derivate und verwandte Heterocyclen. II. Synthese von 1-aminoalkyl-2-benzyl-benzimidazolen. . Helvetica Chimica Acta . 1960 . 43 . 3 . 800–809 . 10.1002/hlca.19600430323 .
  2. Vandeputte M, Van Uytfanghe K, Layle N, Germaine DS, Iula D, Stove C . Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of nitazene new synthetic opioids. . Authorea . 12 November 2020 . 10.22541/au.160520665.59016513/v1 . 234646245 .
  3. Ujváry I, Christie R, Evans-Brown M, Gallegos A, Jorge R, de Morais J, Sedefov R . DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles . ACS Chemical Neuroscience . 12 . 7 . 1072–1092 . April 2021 . 33760580 . 10.1021/acschemneuro.1c00037 . 232356192 .
  4. Lamy FR, Daniulaityte R, Barratt MJ, Lokala U, Sheth A, Carlson RG . "Etazene, safer than heroin and fentanyl": Non-fentanyl novel synthetic opioid listings on one darknet market . Drug and Alcohol Dependence . 225 . 108790 . August 2021 . 34091156 . 10.1016/j.drugalcdep.2021.108790 . 235362241 .
  5. Sisco E, Burns A, Moorthy A . Development and Evaluation of a Synthetic Opioid Targeted Gas Chromatography Mass Spectrometry (GC-MS) Method. . Journal of Forensic Sciences . 2021 . 66 . 6 . 2369–2380 . 10.33774/chemrxiv-2021-0pcnq. 34459514 . 9922096 . 240520700 .

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