Methylquercetagetin 6-O-methyltransferase explained

methylquercetagetin 6-O-methyltransferase
Ec Number:	2.1.1.84
Cas Number:	96477-60-0
Go Code:	0030759

In enzymology, a methylquercetagetin 6-O-methyltransferase is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone

\rightleftharpoons S-adenosyl-L-homocysteine + 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone, whereas its two products are S-adenosylhomocysteine and 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase. Other names in common use include flavonol 6-O-methyltransferase, flavonol 6-methyltransferase, 6-OMT, S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone, and 6-O-methyltransferase.

References

• De Luca V, Ibrahim RK . 1985 . Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases . Arch. Biochem. Biophys. . 238 . 596 - 605 . 3994393 . 10.1016/0003-9861(85)90205-X . 2 .
• De Luca V, Ibrahim RK . 1985 . Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases . Arch. Biochem. Biophys. . 238 . 606 - 18 . 3994394 . 10.1016/0003-9861(85)90206-1 . 2 .