7-Methylguanosine Explained

7-Methylguanosine (m⁷G) is a modified purine nucleoside. It is a methylated version of guanosine and when found in human urine, it may be a biomarker of some types of cancer. In the RNAs, 7-methylguanosine have been used to study and examine the reaction evolving methylguanosine. It also plays a role in mRNA as a blocking group at its 5´-end.^[1]

See also

• METTL1
• 23S rRNA (guanine2445-N2)-methyltransferase
• 16S rRNA (guanine527-N7)-methyltransferase

External links

• Metabocard for 7-Methylguanosine (HMDB01107), Human Metabolome Database, University of Alberta

Notes and References

1. 1739950 . 1992 . Reynaud . C . Bruno . C . Boullanger . P . Grange . J . Barbesti . S . Niveleau . A . Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodies . 61 . 3 . 255–62 . Cancer Letters . 10.1016/0304-3835(92)90296-8.