Methoxpropamine Explained

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist^[1] that is closely related to substances such as methoxetamine and PCPr.^[2] It has been sold online as a designer drug, first being identified in Denmark in October 2019,^[3] and is illegal in Finland.^[4]

See also

• Methoxmetamine
• Methoxyketamine
• MXiPr
• SN 35210

Notes and References

1. Irie T, Yamazaki D, Kikura-Hanajiri R . A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice. . Forensic Toxicology . July 2021 . 39 . 2 . 474–80 . 10.1007/s11419-021-00571-0 . 232273277 .
2. Goncalves R, Castaing N, Richeval C, Ducint D, Titier K, Morvan E, Grélard A, Loquet A, Molimard M . 6 . Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat . Forensic Science International . 333 . 111215 . April 2022 . 35151938 . 10.1016/j.forsciint.2022.111215 . 246685658 . free .
3. Web site: EU Early Warning System Situation Report. Situation report 1 . June 2020 . European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) .
4. Web site: Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista . Government decree on psychoactive substances banned from the consumer market . Finlex Data Bank . Finnish Ministry of Justice . fi .