Methanesulfonate monooxygenase explained

Methanesulfonate monooxygenase
Ec Number:1.14.13.111

Methanesulfonate monooxygenase (mesylate monooxygenase, mesylate,reduced-FMN:oxygen oxidoreductase, MsmABCD, methanesulfonic acid monooxygenase, MSA monooxygenase, MSAMO) is an enzyme with systematic name methanesulfonate,NADH:oxygen oxidoreductase.[1] [2] This enzyme catalyses the following chemical reaction

methanesulfonate + NADH + H+ + O2

\rightleftharpoons

formaldehyde + NAD+ + sulfite + H2O

Methanesulfonate monooxygenase is a flavoprotein.

Notes and References

  1. de Marco P, Moradas-Ferreira P, Higgins TP, McDonald I, Kenna EM, Murrell JC . Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora . Journal of Bacteriology . 181 . 7 . 2244–51 . April 1999 . 10094704 . 93639 .
  2. Higgins TP, Davey M, Trickett J, Kelly DP, Murrell JC . Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme . Microbiology . 142 (Pt 2) . 251–60 . February 1996 . 8932698 . 10.1099/13500872-142-2-251 . free .

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