Mesityl bromide is an organic compound with the formula (CH3)3C6H2Br. It is a derivative of mesitylene (1,3,5-trimethylbenzene) with one ring H replaced by Br. The compound is a colorless oil. It is a standard electron-rich aryl halide substrate for cross coupling reactions.[1] With magnesium it reacts to give the Grignard reagent,[2] which is used in the preparation of tetramesityldiiron.
It is prepared by the direct reaction of bromine with mesitylene:[3]
(CH3)3C6H3 + Br2 → (CH3)3C6H2Br + HBr