Medroxyprogesterone caproate explained

Medroxyprogesterone caproate (MPC) is a progestin and a progestogen ester which was synthesized in 1958 but was never marketed.[1] [2] It has been confused with hydroxyprogesterone caproate (OHPC) and medroxyprogesterone acetate (MPA) in a number of publications.[3] [4] [5] [6] [7] [8] [9] [10] [11] [12] In addition to MPA and OHPC, analogues of MPC include chlormadinone caproate, gestonorone caproate, megestrol caproate, and methenmadinone caproate.

See also

Notes and References

  1. Babcock JC, Gutsell ES, Herr ME, Hogg JA, Stucki JC, Barnes LE, Dulin WE . 6α-Methyl-17α-hydroxyprogesterone 17-acylates; a new class of potent progestins. Journal of the American Chemical Society. 80. 11. 1958. 2904–2905. 0002-7863. 10.1021/ja01544a079.
  2. Barton DH, Taylor WC . 510. Photochemical transformations. Part IV. The photochemistry of prednisone acetate. Journal of the Chemical Society (Resumed). 1958. 2500–2510. 0368-1769. 10.1039/jr9580002500.
  3. Pasqualini JR, Paris J, Sitruk-Ware R, Chetrite G, Botella J . Progestins and breast cancer . The Journal of Steroid Biochemistry and Molecular Biology . 65 . 1–6 . 225–235 . April 1998 . 9699877 . 10.1016/S0960-0760(98)00028-4 . 28416130 .
  4. Pasqualini JR, Ebert C . Biological effects of progestins in breast cancer . Gynecological Endocrinology . 13 . Suppl 4 . 11–19 . June 1999 . 12227897 . 10.1080/gye.13.s4.11.19 .
  5. Pasqualini JR, Chetrite GS . Biological responses of progestogen metabolites in normal and cancerous human breast . Hormone Molecular Biology and Clinical Investigation . 3 . 3 . 427–435 . December 2010 . 25961215 . 10.1515/HMBCI.2010.066 . 41680565 . free .
  6. Lantta M, Kahanpää K, Kärkkäinen J, Lehtovirta P, Wahlström T, Widholm O . Estradiol and progesterone receptors in two cases of endometrial stromal sarcoma . Gynecologic Oncology . 18 . 2 . 233–239 . June 1984 . 6735266 . 10.1016/0090-8258(84)90031-3 .
  7. Book: Gusberg SB, Shingleton HM, Deppe G . Female genital cancer. 1988. Churchill Livingstone. 978-0-443-08525-3. 374.
  8. Book: Proceedings. 1970. American Cancer Society and National Cancer Institute of the U.S. Public Health Service, Federal Security Agency.. 376.
  9. Book: Nichols DH, Evrard JR . Ambulatory Gynecology. 1985. Harper & Row. 978-0-06-141815-0. 518.
  10. Book: Goodman LS, Gilman A . Goodman & Gilman's the Pharmacological Basis of Therapeutics. 1996. McGraw-Hill, Health Professions Division. 978-0-07-026266-9. 1427,1823,1858.
  11. Book: Endokrinologie. 1969. Johann Ambrosius Barth Verlag.. 431.
  12. McKinnon AO, Tarrida Del Marmol Figueroa S, Nobelius AM, Hyland JH, Vasey JR . Failure of medroxyprogesterone caproate to maintain pregnancy in ovariectomised mares. . Equine Vet J . 1993 . 25 . 2 . 158–160 . 10.1111/j.2042-3306.1993.tb02928.x . 8467776 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Medroxyprogesterone caproate".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.