Mannosylglucosyl-3-phosphoglycerate synthase explained

Mannosylglucosyl-3-phosphoglycerate synthase
Ec Number:	2.4.1.270

Mannosylglucosyl-3-phosphoglycerate synthase (MggA) is an enzyme with systematic name GDP-mannose:2-O-(alpha-D-glucosyl)-3-phospho-D-glycerate 2-O-alpha-D-mannosyltransferase.^[1] This enzyme catalyses the following chemical reaction

GDP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate

\rightleftharpoons GDP + 2-O-[2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate

The enzyme is involved in synthesis of 2-[2-O-(alpha-D-mannopranosyl)-alpha-D-glucopyranosyl]-D-glycerate.

Notes and References

1. Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS . Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis . Journal of Bacteriology . 192 . 6 . 1624–33 . March 2010 . 20061481 . 2832527 . 10.1128/JB.01424-09 .