Malotilate Explained

Malotilate (INN) is a drug that has been used in studies for the treatment of liver disease. It has been shown to facilitate liver regeneration in rats.^[1]

References

• Bührer M, Le Cotonnec JY, Wermeille M, Bircher J . Treatment of liver disease with malotilate. A pharmacokinetic and pharmacodynamic phase II study in cirrhosis . Eur. J. Clin. Pharmacol. . 30 . 4 . 407–16 . 1986 . 3743616 . 10.1007/BF00607952. 19898827 .
• Siegers CP, Pauli V, Korb G, Younes M . Hepatoprotection by malotilate against carbon tetrachloride-alcohol-induced liver fibrosis . Agents Actions . 18 . 5–6 . 600–3 . August 1986 . 3766314 . 10.1007/BF01964970. 3213262 .
• Younes M, Siegers CP . Effect of malotilate on paracetamol-induced hepatotoxicity . Toxicol. Lett. . 25 . 2 . 143–6 . May 1985 . 4002245 . 10.1016/0378-4274(85)90074-8.

Notes and References

1. Acceleration of Liver Regeneration by Malotilate in Partially Hepatectomized Rats. Niwano Y, Katoh M, Uchida M, Sugimoto T. 10.1254/jjp.40.411. Japanese Journal of Pharmacology. 40. 3 . 1986 . 411–415. 2423727. free.